Ugolino and His Sons

He won the Prix de Rome in 1854 which empowered him to live in Rome (1856 †1862). During that time he was affected by crafted by Italian stone workers of the Renaissance time frame, for example, Michelangelo, Donatello, and Andrea Del Verrocchio. He additionally began to build his emphasis of studies on complex figures and bas-reliefs. His enthusiasm drove him to begin cutting a few pieces on marble before the celebrated masterpiece â€Å"Ugolino and His Sons†. Carpeaux was considered as one of the standard craftsmen in Eclecticism.This development needed to surpass Neoclassicism and Romanticism and furthermore portrayed the ombination, in a solitary work, of components from various authentic styles. Carpeaux got numerous distinctions during his lifetime until two months before he passed on rashly of malignant growth at 48 years old in Courbevoie in 1875 CE. The model snows (Figure 1 a man sitting on a stone cu tted witn chains in his legs. The man's outward appearances a ppeared as pain while gnawing the tip of a portion of his fingers. The wrinkles on his eyes with his twisted toes on one another gave the feeling of a confused circumstance the man was put in.Surrounding him, there're four ifferent-matured children; two of them on the left half of their dad's situation, as they gave the feeling of taking a gander at their dad asking. Also, on the correct side, there're the two different children where the littlest child fell on the ground looking dead. The figure portrays the story of a trickster who was the Count of Donoratico and was detained by the diocese supervisor Ruggieri degli Ubaldini in the late thirteenth century Oune 1288). The diocese supervisor detained Ugolino with his children and grandsons in the â€Å"Tower of Hunger†.Also, the ecclesiastical overseer requested the warriors to toss the keys of Ugolinds rison in the Arno River so that it is extremely unlikely for them to be liberated. They were condemned to be left to starve in February 1289. Ugolino had this prophetic dream of the ecclesiastical overseer and his warriors as the master and huntsman slaughtering the wolf the wolf fledglings (Ugolino and his posterity). Ugolino had his heart-broken for hearing his children wailing in their rest requesting bread. He likewise kept his sentiments inside, he had never sobbed, and he used to watch his children sobbing yet him feeling confused deadened thinking.Yet his posterity dreams couldn't fill their stomach. Ugolinds kids began to ook at him, asked why he ended up looking like a stone, gnawing his fingers and twisting his toes of one leg on the other one. For them, they imagined that their dad is starving Just like them or perhaps more however for Ugolino himself, he was gnawing his fingers in anguish, sobbing inside for not having the option to take care of his posterity. Subsequently, they began to offer their bodies to their dad so he can eat and survive.After hardly any days, his posterity began to tu mble down dead one by another till the keep going one kicked the bucket on the 6th day. This part is cited from â€Å"The Divine Comedy, Vol. l: Inferno Canto 33) †Dante Alighieri†. It delineates snapshots of death of Ugolinds posterity and the puzzle behind the chance of Cannibalism: â€Å"l quieted myself to make them less miserable. That day we sat peacefully, and the following day. O barbarous Earth! You ought to have gulped us! The fourth day came, and it was on that day My Gaddo fell prostrate before my feet, Crying: Why dont you help me?

Optimization Of Supercritical Carbon Dioxide Extraction Biology Essay Essay Example

Improvement Of Supercritical Carbon Dioxide Extraction Biology Essay Improvement using reaction surface methodological examination for the extractions of phenoplasts from Citrus hystrix foliage was done by supercritical liquid extraction. The impacts of CO2 rate, extraction power per unit region and extraction temperature on yield, whole phenolic substance and Diphenyl-picrylhydrazyl-IC50 were assessed and contrasted and ethanol extraction. Ethanol imbuements and ideal SFE conditions were broke down with HPLC. Among the three factors considered, extraction power per unit zone had the most significant impact on the yield, TPC and DPPH-IC50 of the imbuements, trailed by CO2 rate and extraction temperature. The ideal states of power per unit region, CO2 rate and temperature were at 267 bars, 18 g/min and 50oC, severally. The yield, TPC and DPPH-IC50 got were 5.06 % , 116.53 milligram GAE/g imbuement and IC50 of 0.063 mg/ml, severally. These qualities were respectably close to their contrary number of anticipated ( p gt ; 0.05 ) . Better concealment and T PC were acquired using SFE technique though higher yield and phenolic acids were seen with ethanol extraction. We will compose a custom exposition test on Optimization Of Supercritical Carbon Dioxide Extraction Biology Essay explicitly for you for just $16.38 $13.9/page Request now We will compose a custom exposition test on Optimization Of Supercritical Carbon Dioxide Extraction Biology Essay explicitly for you FOR ONLY $16.38 $13.9/page Recruit Writer We will compose a custom article test on Optimization Of Supercritical Carbon Dioxide Extraction Biology Essay explicitly for you FOR ONLY $16.38 $13.9/page Recruit Writer The frightening life way and less adjusted supplement utilization all around mostly because of high centralizations of free lipid gatherings, both in supplement ( in vitro ) and in vivo after supplement utilization has given to the interest to take a gander at cell reinforcements as a practical fixing in supplement. Man-made cancer prevention agents, for example, butylated hydroxytoluene ( BHT ) , butylated hydroxyanisole ( BHA ) , tertiary-butyl hydro-quanone ( TBHQ ) and propyl gallate ( PG ) , are traditional supplement cell reinforcements. Because of wellbeing issues, customer concerns and expanding regulative assessment ( Jamilah et al. , 2009 ; Shahidi. , 1997 ) refering man-made cancer prevention agents, the chance of common cell reinforcements as alternatives is strongly looked into. The foliages of Citrus hystrix, referred to locally as, Limau purut, is utilized in numerous Malayan and South-East Asiatic part neighborhood dishes and medicative readyings. C.hystrix as a poten tial fresh start of normal cell reinforcement was accounted for by Jamilah et Al. ( 1998 ) , Ching and Mohamed ( 2001 ) , Jaswir et Al. ( 2004 ) , Idris et Al. ( 2008 ) , Chan et Al. ( 2009 ) and Butryee et Al. ( 2009 ) . All imbuements were removed using the ordinary dissolvers, for example, ethyl liquor, methyl liquor, propanone and H2O. To deliver mixtures of high phenolic substance and wealthy in cell reinforcements from C. hystrix foliages, requires high extraction productivity impacted by components, for example, iota size, extraction techniques, dissolvable sort, dissolvable fixation, dissolvable to-strong proportion, extraction temperature, power per unit territory and clasp ( Banik et al, 2007 ; Lang et al. , 2001 ; Pinelo et al. , 2005 ; Silva et al. , 2007 ) . Steam distillment and natural dissolver extraction using invasion, maceration and Soxhlet strategies are expectedly utilized for the extraction of bioactive mixes from works beginnings. They are non productive and conservative and this can be overwhelmed by using the supercritical C dioxide ( SC-CO2 ) technique ( Bimakr et al. , 2009 ) . Carbon dioxide ( basic temperature, power per unit zone and thickness ~ 31.18 oC, 72.0 cantina ; 0.47 gcm-3, severally ) is protected, buildup free, non-combustible, in costly and naturally cordial ( Pyo and Oo, 2007 ) . The streamlining of supercritical liquids for the extraction of regular cancer prevention agents and phenolic mixes from the foliages of C.hystrix has non been accounted for. Thus, this review was completed with the point of enhancing the extraction of the cancer prevention agent and phenolic acids from the foliages of C. hystrix using supercritical C dioxide ( SC-CO2 ) liquid extraction by evolving as well as fixing realized factors related with the extraction procedures. 2 Materials and Methods 2.1 Reagents utilized Folin-Ciocalteu Reagent ( FCR ) and 1,1-Diphenyl-2-picryl-hydrazyl ( DPPH ) were bought from Sigma ( St Louis MO USA ) . Carbone dioxide, ( immaculateness 99.99 % ) , joining in a Carbone dioxide plunge tubing chamber, was bought from Malayan Oxygen ( MOX ) , Malaysia. Outright ethyl liquor ( 99.4 % , expository class ) , the qualifier for SC-CO2 technique, acetonitrile and methyl liquor ( HPLC class ) as the traveling stage for HPLC and phenolic acids measures ( vanillic corrosive, syringic corrosive, p-coumaric corrosive, M-cumeric, trans cinnamic corrosive, benzoic corrosive, Gallic corrosive and sinapic corrosive ) were bought from Fisher Scientific Chemical ( Loughborough, England ) . Every other synthetic utilized were either explanatory or HPLC class. 2.2 Preparation of Sample The foliages of C. hystrix were gotten from Pasar Borong, an entire deal showcase at Puchong, Selangor, Malaysia. After coming to at the examination lab, foliages were arranged, washed under running tap H2O, broiler dried at 40AÂ °C for 24h and put away at surrounding temperature off from the obvious radiation. The dried foliages were land simply before extraction in a liquidizer ( MX-335, Panasonic, Malaysia ) for 10s to deliver a pummeling with an approximative molecule size of 0.5mm ( Bimak et al. , 2009 ) . 2.3 Solvent Extraction The phenolic mixes in the C. hystrix leaves powder were separated blending to Jamilah et Al. ( 1998 ) with little changes. The principal measure included absorbing the pummeling 95 % ethyl liquor for 24h at 50oC at an ethyl liquor to flick proportion of 10:1 ( v/w ) . The oil implantation was so separated and assembled by disintegrating at 40oC in the rotating evaporator ( Eyela, A-1000S, Japan ) .When the ethyl liquor was vanished off the concentrated mixture was moved into earthy colored glass bottles, flushed with N and kept at 25oC until use. The extraction was done in triplicate 2.4 Supercritical Carbon Dioxide ( SC-CO2 ) Extraction Supercritical C dioxide ( SC-CO2 ) liquid extraction using the supercritical liquid extractor ( ABRP200, Pittsburgh, PA, USA ) , with a 500 milliliter extractor vas connected, was completed orchestrating to Bimark et Al. ( 2009 ) with little adjustments. The stream pace of CO2 and modifier, extraction temperature, power per unit region and clasp were balanced using ICE bundle combined with the supercritical liquid extractor. The fluid CO2 was pressurized and warmed to the pined for power per unit zone and temperature with the help of power per unit territory siphon ( P-50, Pittsburg, PA, USA ) to make the supercritical area preceding go throughing it into the extraction vas. Supreme ethyl liquor was utilized as the qualifier to better the extraction of phenoplasts from C.hystrix foliages and fixed at a stream pace of 3 milliliters/min for all test processs. The continuation of the idle extraction cut was fixed at 30 min, while the dynamic extraction cut was constant at 90 min. Fifty gms of C. hystrix foliages ( pummeling ) was various with 150g glass globules ( 2.0 millimeter in breadths ) to arrange the stream rate and the blend was put in the extractor vas. The extraction was so performed under arranged test conditions as produced by the reaction surface methodological examination ( RSM ) plan. EtOH was expelled from the imbuements by vacuity vaporization using a rotating evaporator ( Eyela, A-1000S, Japan ) at 40 AÂ °C. The implantations were gathered in the unit of ammo bottle flagon ( twisted with aluminum foil to limit light introduction and along these lines oxidization ) thus positioned in the stove at 40AÂ °C for 30 min before being moved into desiccators for closing invariable weight. Implantations were moved into earthy colored glass bottles, flashed with N and put away in a profound freeze of - 25AÂ °C until more remote investigation. The extractions were done in additional items. 2.5 Determination of Total Phenolic Content ( TPC ) The whole phenolic substance of C.hystrix foliage mixtures was resolved using the Folin-Ciocalteu reagent orchestrating to the technique portrayed by Singletone et Al. ( 1999 ) . An aliquot of the mixture ( 0.5mL ) was placed in 0.5mL of Folin reagent, under diminish noticeable radiation before 10mL ( 7 % ) of Na carbonate was included. The blend was so left in obscurity for 60A min. The optical thickness of the blend was estimated against EtOH ( space ) at 725A nanometers by using an UV-Visible spectrophotometer ( UV-1650PC, Shimadzu, Kyoto, Japan ) . The normalization condition for Gallic corrosive, communicated as Gallic corrosive comparable ( GAE ) in mg/g implantation, was y = 0.0064x + 0.0093 ( R2 = 0.9972 ) . 2.6 Determination of Free Radical Scavenging Activity Free radical rummaging movement of C.hystrix foliage mixtures was estimated blending to the procedure depicted by Ramadan et Al. ( 2006 ) with little changes. A 0.1A milliliter aliquot of toluenic test arrangement at various focuses was included with 0.39A milliliters of new toluenic 1,1-Diphenyl-2-picryl-hydrazyl ( DPPH ) arrangement ( 0.1A millimeter ) . Triplicates were completed for every fixation. The blends were shaken astutely and left in obscurity for 60A min and optical thickness was perused against unadulterated methylbenzene ( clean ) at 515A nanometers using an UV-Visible spectrophotometer ( UV-1650PC, Shimadzu, Kyoto, Japan ) . The free fanatic rummaging movement of implantations was determined as follows: % Inhibition = ( [ Acontrol-Asample ]/Acontrol ) *100 Where AcontrolA =A optical thickness of the cont

Blog Archive MBA Career News Deciding Whether to Apply to Multiple Jobs in the Same Company

Blog Archive MBA Career News Deciding Whether to Apply to Multiple Jobs in the Same Company In this new blog series, our mbaMission Career Coaches offer invaluable advice and industry-related news to help you actively manage your career. Topics include building your network, learning from mistakes and setbacks, perfecting your written communication, and mastering even the toughest interviews. To schedule a free half-hour consultation with one of our mbaMission Career Coaches, click here. Applying for multiple positions at a company can be either an effective strategy or a dangerous one. You need to know your target audience. Will hiring managers view multiple applications as evidence of your lack of focus and commitment, or will they perceive your passion for their company? Before you consider applying to multiple positions within the same company, we suggest you take the following steps: Gather information on the company’s practices regarding multiple applications. Seek advice from networking contacts and/or HR to understand if they look favorably upon the practice or discourage it. Learn more about each position (again, from HR, networking contacts, or peers who have held the position or similar positions), and be sure you have a good grasp of the differences and similarities among the roles. If the roles are similar (same function, skill set, etc.), you have a better reason for applying to multiple positions. Understand whether the positions have the same hiring manager. Research the backgrounds of people who currently serve in each role of interest at your target firm or other firms; use LinkedIn. Are there any trends among their backgrounds? Is your background more similar to one of the positions than the others? Evaluate each position and ask yourself, “Why am I applying for this position?” Can you articulate clear reasons why you are qualified for and interested in more than one role? You do not want to come across like you are just applying to every job that you see without really evaluating how you can contribute to the organization in that role. When you apply, focus on doing the following (these tips apply whether you are submitting one application or multiple): Treat each opening as a unique position, each unrelated to the others. Tailor your resume and cover letter for each application (check out our previous blogs on writing effective resumes and cover letters). Focus on proving that you are a qualified and distinctive candidate for each role. Have you been admitted to business school? If so, do you want to get a head start on defining your career goals? Do you need help preparing for job interviews or learning how to effectively network with your target employers? Or maybe you want to be a top performer in your current role but are unsure how to maximize your potential. Let an mbaMission Career Coach help via a free 30-minute consultation! Share ThisTweet Career Advice MBA Career News

The Civil War - 995 Words

There were many different events that contributed to the start of the Civil War. The Civil war was one based on people and slave rights. It was a compilation of confrontations regarding the institution of slavery. It was a long-standing war where many such as President Lincoln strongly intervened. There were three events, however, that I believe were the most important events leading to the Civil War. These events included The Missouri Compromise of 1820, The Compromise of 1850, and Uncle Tom’s Cabin in 1852. The Missouri Compromise created a moral issue using a simple geographical line, while the Compromise of 1850 led to increased polarization amongst centrist citizens due to the new Fugitive Slave Act. Uncle Tom’s Cabin created conflicting views of slavery between the Northerners who felt it was unethical and the Southerners who believed Uncle Tom’s Cabin was slanderous. The Missouri Compromise was a paramount event that contributed to the beginning of the Civil War. The Missouri Compromise slowly followed the Louisiana Purchase of 1803, where the growth caused Congress to need to establish a new slavery policy. This policy was needed to guide slavery expansion into the new territory of the west. A vicious national debate erupted, however, as Missouri applied for statehood as a slave state. Moral issues began to ensue facing the growth of slavery and Missouri’s pro-slavery Congressional majority. The Missouri Compromise was established as Congress made aShow MoreRelatedThe War Of The Civil War921 Words   |  4 PagesThere are no doubts that acts of war can have a negative impact on the individuals involved. There are countless stories of the soldiers’ experiences in the war, and how it affected their lives, families, and attitudes. However, there is a large demographic that is hardly accounted for: children, specifically during the Civil War era. Understanding the children that lived in the time of the Civil Wa r is important because it affected their future careers, shaped their attitudes towards race, and affectedRead MoreCivil War And A Revolution1196 Words   |  5 Pagesthat a civil war is going on there. On the other hand, others argue that it is a revolution against oppression that has been brutally responded to. Evaluating the situation in Syria requires solid understanding of specific terms of a civil war and a revolution. Also, is there a general consensus on what a civil war or a revolution is? Can the situation in Syria simply be classified into one of these two? The first important thing to know is that there is no single definition of a civil war that historiansRead MoreThe War Of The Civil War964 Words   |  4 Pageswasn’t one sole cause of the Civil War but there were many events that took the country to war and put brother against brother and states against states. Abraham Lincoln wanted to preserve the union and that could only be attained by civil war. Slavery which was an underlying cause for the war played its role in the division that divided the North against the South. Ultimately the preservation of the union, slavery and the consequences and conflicts leading to the Civil War all rested on President Lincoln’sRead MoreThe War Of The Civil War1522 Words   |  7 PagesCosts The war produced about 1,030,000 casualties, including about 620,000 soldier deaths—two-thirds by disease, and 50,000 civilians. The war accounted for roughly as many American deaths as all American deaths in other U.S. wars combined. Based on 1860 census figures, 8% of all white males aged 13 to 43 died in the war, including 6% in the North and 18% in the South. Union army dead, amounting to 15% of the over two million who served, was broken down as follows: Notably, their mortality rateRead MoreThe War Of The Civil War1540 Words   |  7 PagesOver the course of the Civil War, approximately three million men (and a handful of women disguised as men) served in the armed forces. By comparison, before the war, the U.S. Army consisted of only about 16,000 soldiers. The mobilization that took place over the four years of the war touched almost every extended family North and South and affected the far reaches of the country that had split in two. By war’s end, approximately 620,000 men had died, an estimate that is currently undergoing scrutinyRead MoreThe War Of The Civil War777 Words   |  4 PagesThe widespread violence that turned into the Civil War began with the election of 1860. Abraham Lincoln won the election of 1860 without a single vote from the states below the Ohio River. South Carolina was the first state to respond to Li ncoln’s election. On December 20, 1680, South Carolina seceded from the Union. South Carolina was the first of the â€Å"Original Seven† who seceded from the Union, including Mississippi, Florida, Alabama, Georgia, Louisiana, and Texas. This became known as â€Å"secessionRead MoreThe War Of The Civil War1039 Words   |  5 PagesThe civil war is by far the bloodiest war in American history. In the four deadly years of war, over six-hundred thousand Americans were killed. Many disputes that led to the civil war. These conflicts started under President James Buchanan who was a Democrat elected in the election of 1856. The issue of slavery, states’ rights, the abolitionist movement, the Southern secession, the raid on Harper’s Ferry, the election of Abraham Lincoln all contributed to the start of the civil war. The civil warRead MoreThe War Of The Civil War Essay1444 Words   |  6 PagesThe story of this outlaw originated during the Civil War years, Apr il 12,1861-May 9, 1865. The War were the rich sat and watched, while the poor died. A War that wanted to keep black people as slaves permanently by the South (Confederates). Newton Knight quickly grew unhappy with the situation that the people of Jones County, where he was originally from were in. He also did not approved of slavery at all. Newt was the Outlaw who freed Jones County s people, whites and blacks alike when they mostRead MoreThe War Of The Civil War1284 Words   |  6 PagesEnglish 30 January 2015 The Civil War There are many facts most people generally do not know about the Civil War, so much research is needed to improve one’s knowledge about the Civil War. Authors such as: Robert G. Lambert, Rustle B. Olwell, and Kay A. Chick were all helpful in this research. Many people think that everyone on the Union side of the war believed that blacks should be equal to whites. Most people also think that everyone on the Confederate side of the war believed in slavery. SomeRead MoreThe War Of The Civil War1723 Words   |  7 PagesThe Civil War is by far the bloodiest war in American history. In the four deadly years of war, over six-hundred thousand Americans were killed. Many disputes that led to the civil war. These conflicts started even before the presidency of James Buchanan, who was a Democrat elected in the election of 1856. The issue of slavery, states’ rights, the abolitionist movement, the Southern secession, the raid on Harper’s Ferry, the election of Abraham Linc oln all contributed to the start of the Civil War

Joseph Conrad s Heart Of Darkness - 1488 Words

Joseph Conrad’s s novel Heart of Darkness portrays an image of Africa that is dark and inhuman. Not only does he describe the actual, physical continent of Africa as â€Å"so hopeless and so dark, so impenetrable to human thought, so pitiless to human weakness†, (Conrad 154) as though the continent could neither breed nor support any true human life. Conrad lived through a time when European colonies were scattered all over the world. This phenomenon and the doctrine of colonialism bought into at his time obviously influenced his views at the time of Heart of Darkness publication. Very few people saw anything amiss with colonialism in Africa and the African people. From a Eurocentric point of view, colonialism was the natural next-step in any powerful countries political agenda. The colonizers did not pay heed to the native peoples in their territories, nor did they think of the natives as anything but savages. In the Heart of Darkness, Joseph Conrad uses Marlow to cont radict the acts of man and the destruction they brought forth to Africa and their people. Conrad shows, through fiction, that the blindness and lack of morality in Africa allowed for the release of the darkness from the hearts of the colonists. In the opening of his novel, Heart of Darkness, Conrad, through Marlow, establishes his thoughts on colonialism. He says that conquerors only use brute force, nothing to boast of† (Conrad 13) because it arises, by accident, from another s weakness. Marlow compares hisShow MoreRelatedJoseph Conrad s Heart Of Darkness957 Words   |  4 Pages Chinua Achebe’s controversial essay published in 1977 focuses on the racist views woven into Joseph Conrad’s 1899 novella, Heart of Darkness. Achebe claims that Conrad uses many western stereotypes of Africa and subtly weaves them below the surface of his writing. However, due to the popularity of the novella and the skill of Conrad, his racist views go undetected. The most obvious indicator of Conrad’s racist views is the depictions of the people. They are described as â€Å"savage creatures,† yet Conrad’sRead MoreJoseph Conrad s Heart Of Darkness925 Words   |  4 PagesIn the heart of darkness sails a ship with sailors, seamen, businessmen, and cannibals; savages as one would say. The businessmen conduct the seamen, the seamen order the sailors, and the sailors command the cannibals. On this diminutive yawl sailing deeper and deeper into the hazy, enigmatic heart of darkness lies a small caste system, with the managers above and the savages belo w. The story of Charlie Marlow on this ship is unveiled in Joseph Conrad s novella, Heart of Darkness, along with inklingsRead MoreJoseph Conrad s Heart Of Darkness988 Words   |  4 Pagesthe late 1890’s, Joseph Conrad’s Heart of Darkness holds two different meanings. Heart of Darkness is both a metaphor for a psychological side of man, and an allusion to Africa. The title suggests both a physical and mental reference. During the time the novel takes place, Africa was called the dark continent. This was because little was known about Africa, and it was rather a mystery to Europeans. The main character in the novel, Marlow describes Africa as â€Å"a place of darkness† (Conrad 43). He alsoRead MoreAnalysis Of Joseph Conrad s Heart Of Darkness 1396 Words   |  6 PagesShelly Pyakurel Ellen Stockstill English 4 DC 27 April 2015 Research Paper Heart of Darkness is a novel by Joseph Conrad that centers on Marlow, a man who goes to the Congo for a job opportunity. He meets a man named Kurtz, who is well known by many. Once he gets to the Congo, he sees colonialism first-hand. He sees that the natives of the country were practically enslaved and forced to work under very harsh conditions. The two major characters of the novel are Marlow and Kurtz. There are many minorRead MoreAnalysis Of Joseph Conrad s Heart Of Darkness1504 Words   |  7 Pagescontrol over others and can be found in both people and objects. In Joseph Conrad’s Heart of Darkness the main character and narrator Marlow identifies a force within ivory that conveys a sense power within the enigmatic Mr. Kurtz. The African ivory trade was flourishing in the early 1900’s. Obtaining the precious object transformed some into greedy connoisseurs with endless intentions to get their hands on all of the continents ivory. Conrad shows that the power that i s emitted from the ivory falls intoRead MoreAnalysis Of Joseph Conrad s Heart Of Darkness963 Words   |  4 Pagespeople. Heart of Darkness, by Joseph Conrad, can be criticised through many different lenses. Though Natives are a large part of Conrad’s narrative of European atrocities in the Congo, his treatment of Congolese Natives throughout the book show them to be nothing more than props. Conrad skews Natives language, culture and intelligence to fit Europeans schema for Africa and Africans. Conrad’s Heart of Darkness is placed in a colonized Congo. ...despite Heart of Darkness s (Joseph Conrad) obviousRead MoreAnalysis Of Joseph Conrad s Heart Of Darkness1555 Words   |  7 PagesAlthough the author Joseph Conrad never met the German philosopher Gottfried Wilhelm Leibniz, who died more than a century before Conrad’s birth, their distinct philosophies still have numerous points of intersection, suggesting some fundamental truths within the structure of the human reality. Through the novella, Heart of Darkness, Conrad details his perspectives on the faults of man and reality as a whole, with views often coinciding with many of Leibniz’s own, as found in his numerous philosophicalRead MoreAnalysis Of Joseph Conrad s Heart Of Darkness1080 Words   |  5 Pages1 Kathrine Carrasquillo Dr. David Mulry Engl 2112 Feb 13, 2017 Who is Mr. Kurtz, and what does Conrad use him for? Mr. Kurtz is the main character in Joseph Conrad s English novella, Heart of Darkness. There is no proof that Mr. Kurtz is based on a real person, so it is assumed that he is a made up character. When Mr. Kurtz is first introduced the audience learns that he is a Belgian ivory trader and he was sent to Africa by his employer for work. At first glance, Mr. Kurtz just represents a normalRead MoreAnalysis Of Joseph Conrad s The Heart Of Darkness 1801 Words   |  8 PagesAlly Jones Professor Smith English 1302 November 18, 2014 Female Roles in Joseph Conrad s the Heart of Darkness: In regards to Joseph Conrad’s Heart of Darkness, many literature reviews focus on the motifs of Imperialism, the symbolism of darkness and fog, or the aspect of racism in Conrad’s work. During the era which Conrad wrote, England was going through the Victorian Era, which was marked by a shift in views on morality. The term â€Å"Victorian morality† is used today to describe values whichRead MoreAnalysis Of Joseph Conrad s Heart Of Darkness 1713 Words   |  7 PagesMonth: January 2014 Name: Faris Khan Period: 3 Title: Heart of Darkness Author: Joseph Conrad Date started/date completed: 1/19 - 1/28 Pages read: 96/96 (Including the ten page introduction, 106/96) Rating of book (1-10): 9/10 Above you rated this book. Explain in detail why you gave this book that score: Author Joseph Conrad uses a very interesting method of narration in his novel, Heart of Darkness. The novel itself is written in first person, from the perspective of an unnamed sailor aboard

The Bridge Between The Middle Ages And The Renaissance Era...

History is a vast ocean of time and regions, yet some are seen as more influential than others.The Renaissance can be described as an era in which science and culture mixed, therefore creating waves of innovation that rippled throughout the entire planet. In the 14th century, Rome had long fallen, and centuries of Christianity had taken Europe. Crusades were led across vast regions, as well traders traveling to the east and discovering new goods to sell and trade.This began exploration into other cultures, particularly past ideologies. Early Rome and ancient Greece were studied and the studies of Pluto were rediscovered. This new interest was accelerated by The Great Papal Schism of 1378 in which three men decreed themselves the Pope at the same time. During this period of religious uncertainty a movement of â€Å"Humanism† was rediscovered. People had the desire to study forgotten texts, and learn the ideas of the past. The bridge between the Middle Ages and The Renaissance e ra were beginning to be built. This time period of rediscovery is known as the â€Å"Proto-Renaissance† and lasted between 1200-1400. Where it all began, the influence of humanism, and the artists that attributed will be the subject of this essay. During the period of Proto-Renaissance the entirety of Europe established different developments in each of it’s regions, yet Florence and Sienna experienced copious amounts of innovation. Artists and Scholars searched, studied and emulated the teachings of theShow MoreRelatedThe Renaissance : A Rebirth Of The Ideas Of Ancient Greece923 Words   |  4 PagesThe Renaissance was a rebirth of the ideas of ancient Greece and Rome that began in the City States of Italy during the 14th century. The cultural resurgence began a new style of living in Europe after the horrors of the black death, and is seen as the beginning of the culture of the modern world. As Wassace K. Ferguson put in his book The Renaissance, the Italian artists grew tired of the darkness of Medieval Times and began to turn to the brighter times found in the classical ages (Doc 7). TheRead MoreComparing Art And The Baroque Eras989 Words   |  4 PagesComparing Art of the Renaissance and the Baroque Eras The Renaissance and the Baroque eras created some of the most famous works of art produced in the world. The two eras expressed differences in style and theme, but they also have many characteristics in common. To better understand the similarities of the eras it will be described by the characteristics, styles and the influences of each; Renaissance and Baroque works of art. Famous artist from the Renaissance era were Leonard da Vinci and MichelangeloRead More Middle Ages Essay712 Words   |  3 PagesMiddle Ages The history of the modern world derives from thousands of years of human history. Embedded in its history are the many eras of man which have constructed our modern learning, art, beliefs, and order. The middle ages, although represented as â€Å"dark†, backwards, and idle, were in fact a bridge linking the classical and modern world. Medieval society may not have been in a sense glorious, but the era of itself was a prime foundation of the modern world’s newfound stability, a revivalRead MoreComparison of Two Historical Art Periods1131 Words   |  5 PagesPeriods: Middle Ages (Gothic) and Renaissance Architecture Christina Plunkett Western Governors University IWT1 Humanities Task 1 Gothic style came about in the middle of the twelfth century. It was named after the Goths that controlled France during that time. It was developed as a result of Christian ideals. Christian leaders wanted big, tall, ornate churches to represent their strong faith. Later it was also used for non-religious buildings such as castles, walls, bridges, and gatesRead MoreEssay on Unraveling the Mystery of William Shakespeare582 Words   |  3 Pagesconsequences of the Renaissance. In fact his outstanding work was the direct result of the Renaissance. In order to understand how Shakespeare came to be, there is first a need to understand exactly what the Renaissance was. The original Italian word, ‘Rinascimento’, means ‘rebirth’ (Jonah Wilberg). This refers of course to the rebirth of learning. The Renaissance was a cultural movement that spread all over Europe and was considered the division between the Middle Ages and the Modern Era (Fabio CastellanRead MoreThe Period Of Rome And Greece1467 Words   |  6 Pagesof reference after the fall of Rome and Greece known as â€Å"the Middle Ages† also defined as the Dark Ages. Dark Ages denote customary light-versus-darkness; the contrast to darkness reveals a period void of light, a period of intellectual darkness. Some segments of Europe during this period lacked sufficient historical and written archive records. The conception of the Dark Age originated with the Italian scholar, poet, and Renaissance humanist David Petrarch (Francesco Petrarca) in the 1330s. Read MoreThe Renaissance And The Middle Ages1516 Words   |  7 PagesThe Middle Ages were regarded as a dark and desolate time period in history. Society during this time had no social progress, incessant wars, extreme violence, and no improvement to intellect or education. The Renaissance marked the end of the Middle Ages lasting roughly from the early 1400s to the 17th century. The Renaissance was exceptionally different from the Dark Ages because the human intellect, social climate, and the beliefs of Renaissance men was the opposite of the Middle Ages. ActingRead MoreCompare And Contrast Different Literature Periods1452 Words   |  6 Pageswill demonstrate the relation between the literature and social events, and how authors affected and contributed to form those periods, also I will try to compare two different literature periods. The Renaissance (rebirth period) The Renaissance is an era started in Italy and it came to England in the sixteenth century that made an end to the dark ages whose knew before it. This period became the bridge who access between the middle ages and the modern history. Renaissance is a French word means rebirthRead MoreA Short Note On The Arch Of Constantine887 Words   |  4 PagesEmpire. His legacy is known for his bold changes and accomplishments in uniting the empire making it become more powerful once again and his outlawing of paganism, and curbing Christians from persecutions. The Arch of Constantine was erected between 312 and 315 AD., in Rome adjacent to the Coliseum to commemorate Constantine’s triumph over Maxentius in a victory that united the empire and insured its transition into the Eastern Roman Empire known as the Byzantine Empire, with its capital ConstantinopleRead MoreIf Rome Never Fell2888 Words   |  12 PagesBC. The republic consisted of citizens voting on representatives called senators, much like America today; However, to be elected one was traditionally a noble. After struggles for equality within the government, Rome pulled together and began its age of great expansion. Rome began taking control of the entire Mediterranean region, and Europe and could not stop its conquest. In its prime the Roman empire stretched as far west as Portugal to Persia in the east, and as far north as Britain to North

Introductory Course in Economics free essay sample

Price Theory and Applications 2. 0 Theory of Demand and Supply Concept of demand Law of demand and demand curve Demand for substitute goods and complementary goods Demand for normal goods and inferior goods Determinants of demand Change in demand and change in quantity demented Concept of supply Law of supply and supply curve Determinants to supply and change in quantity supplied quantity 2. 1 formula elasticity revenue curve of demand market period elasticity of demand and income elasticity Cross price elasticity of demand demand for substitutes and complementary goods Income elasticity of demand for normal and inferior goods 2. 2 and supply and elasticity concepts Regulated prices Change in supply Market equilibrium Supply and demand equality Equilibrium price and Surpluses and shortages Elasticity of Demand and Elasticity of Demand Price elasticity of Demand Price elasticity coefficient and Arc elasticity and point Price elasticity and total Determinants of price elasticity Elasticity of Supply Price elasticity of Supply Price elasticity of supply and Concepts of cross price Cross price elasticity of Application of demand Price ceilings and shortages Price floors and surpluses Elasticity and pricing power Elasticity and Indirect taxation and subsidies McConnell, Chi. We will write a custom essay sample on Introductory Course in Economics or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page 3 18; Hardwire, Chi. 3 5 and Costs profits costs economic profit Production costs and relationships Variable costs Marginal cost and Total cost marginal and total cost curves Marginal product and Total product marginal and total product curves Diminishing Returns 3. 2 Costs and relationships Chap. 22; Hardwire, Chap. 2 Renumbers Chi 3 4; 3. Theory of Production 3. 0 3. 1 Economic costs and Explicit and implicit Normal profit and Short-Run Fixed costs and Average cost, Average, Average product, Law of Long-Run Production Firm size and costs The long run cost curve Economies of scale Returns to scale Renumbers Chi. 6; McConnell, Market Structures pure competitive market and its relevance faced by competitive firm 4. 0 Pure Competition Characteristics of Pure competition Demand curve Output and profit mastication in the short run and long run by the competitive firm 4. 1 monopoly determination Pure Monopoly Characteristics of pure Barriers to entry Monopoly demand curve Output and price

Truss Essay free essay sample

Truss Essay If I was building a 10 pitch roof I would use a roof truss rather than using a rafter. A roof truss is a rigid, strong frame work made up of wood members, such as 2† X 4†s, fastened and held together by metal connector plates. A roof truss consists of one or more triangular units constructed of straight pieces that are connected at the ends by joints. Personally roof trusses are superior due to its number of different designs, they are very strong, and lastly they are installed quickly. Wood trusses come in variety of different designs. They are used to make almost any building in the world because of its vast designs. When using trusses I would be satisfied with my house because I get to have the roof of my choice. Trusses also give an advantage to uniqueness in a house because they all won’t look the same. We will write a custom essay sample on Truss Essay or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page That is why I would prefer a truss rather than a rafter. Trusses are designed to be very strong. They have a high level of strength and capacity. Using a truss roof will allow me to safely place weight on the roof. Having a strong roof is a benefit of a good roof that will last a couple of years. Trusses are so strong they can bare a fire since it takes a long time to burn out and since all the pieces are spaced out it will take a longer time to fall apart giving the people who live in the house time to evacuate. Lastly, another advantage of installing a truss roof is that they are installed quickly. The quicker the process is the less amount of labor cost it takes to spend. Also, trusses aren’t messy the come prefabricated they just need to be installed causing the job site to be much cleaner than a standard job site. If I use a roof truss it will take less time to be put up and if I need to work on other things around the house I will have time, therefore this is another advantage of a truss. In conclusion I would use a roof truss because they are very handy. They come in vast designs causing me to have a say in what choice of roof I want. They have a high level of strength and capacity providing a safe strong roof over my head that will last a couple of years, will bare fires and any other damages. Lastly they are installed very quickly causing the cost of labor to be reduced and less mess on job site. Roof trusses are prefabricated roof frames designed to provide a fancy strong roof that is quickly installed.

Global Warming Essay

Global Warming Essay There is plenty of research on Global Warming issues, however, scholar’s over the world are far from unanimity on its root causes and ways of prevention. Global warming  is a climatic process, which is related to what seems to be ‘an insignificant increase of global temperature’. At glance the  difference  seems trivial indeed – Earth’s mean surface temperature has increased by some 0.8 since the early 20th century, however, this has triggered a chain reaction and contributed to glacier melting in the Arctic and the Antarctic Penninsula. This, in turn, is leading to the increase of the ocean heat content, which spurs a whole new series of climatic changes. Most of these changes are believed to be human-induced and are most typically contributed to deforestation and carbon dioxide emissions. There is plenty of research on Global Warming issues, however, scholar’s over the world are far from unanimity on its root causes and ways of prevention. Most scientists, with a 90% probability, tend to agree, that it is a process that is directly related to human activity. To substantiate their claim, they pull out the so-called ‘hockey stick’ graph, which was first introduced by Michael Mann in 1998 and is since widely used by world’s climatologists. GLOBAL WARMING IS A  MYTH The graph reads as follows: during the last nine centuries, global temperature has remained relatively unchanged (which is likened to the shaft of the stick), while during the last century (with the advent of the industrial revolution) the graph curve escalated dramatically (the part that resembles the blade). Such arguments look quite convincing if you compare temperature fluctuations during the nine-hundred-year span to those of the last century. The hockey stick graph has also spurred debate on the validity of the datasets and their interpretation and has lead to the so-called ‘hockey stick controversy’, in which some environmental scientists questioned data and methods used by Michael Mann. Mann’s model ended up being reviewed and analyzed by the National Academic of Sciences, who supported Mann’s initial hypothesis, saying that current temperature levels were unprecedented until at least 1000 years. In years that followed, this model was tested by other scholars who used more sophisticated data sets and statistical methods, and they too confirmed that Mann’s initial model was accurate. More sophisticated data sets and improved methods of research were able to extend the ‘hockey shaft’ as far as 11000 years back, only confirming the initial hypothesis – global warming is a result of human irresponsibility. This essay is a short stub on the extensive topic called ‘Global Warming’. If you need an article written on the topic, feel free to contact us for a custom written essay on any of the global warming issues. We would be happy to find a writer with a background in climatology/ecology who will come up with a top-notch quality product on any of the ‘global warming’ subtopics.

The four management functions in relation to operation management Essay

The four management functions in relation to operation management theory - Essay Example The paper tells that there are four functions that a manager accomplishes in a business organization. These four functions are known as planning, controlling, organizing, and leading. This section of the paper will look at these individual functions closely. Planning involves the "ongoing process of developing the business' mission, and objectives, and how they will be accomplished." The planning process can be used in a broad sense to take into account the whole organization. This will include devising the company's mission and vision. It can also be applied in a specific situation such as the formulation of a strategy to increase the company's market share. Organizing, on the other hand, refers to the creation of the company's organizational structure. This involves determining the functions to be done as well the resources to accomplish them. Organizing also includes how processes will be managed and coordinated. In summary, the organizing function encompasses how managers distrib ute tasks to job holders and focus on division of labor, coordination, control of tasks, and flow of information within the organization. The third managerial function is leading to other writers refer to this function as directing. Leading "is influencing people's behavior through motivation, communication, group dynamics, leadership, and discipline." The real essence of leading is for the manager to equip the employees with their needs to realize the organization's objectives while giving them room to achieve their respective career objectives. Controlling is the managerial function which necessitates the identification of the company's specific goals. Controlling is a "four-step process of establishing performance standards based on the firm's objectives, measuring and reporting actual performance, comparing the two, and taking corrective or preventive action as necessary." Put simply, the controlling function of management is the check and balance system which tries to reveal th e inefficiencies in the strategies employed in realizing the goals of the organization. Controlling is very significant as it tells the managers the loopholes and enables them to correct their systems in order to enhance the company's performance. The operation is one of the functional areas of an organization. Operations management is essentially the area which carefully manages the processes of the company's value chain in order to efficiently produce and distribute its products and servicesÃ'Ž Operations management is indispensable in the functioning of any business organization may it be a small start-up entity or a large manufacturing firm. Operations management deals with the management of the company's core activity. Therefore, the functions of operations managers vary with the major activity of a business entity. The operation manager of a company engaged in the manufacture of children’s toys is basically tasked to oversee the firm’s value chain from the procu rement of raw materials, assembly, sales, and after sales services such as handling of complaints and warranties. On the other hand, the operations managers of a service company like a spa handles day to day activities like management of workforce to service the customers.

Write up Essay Example | Topics and Well Written Essays - 500 words - 1

Write up - Essay Example fasalt and marble schiet which according to Erickson were formed through heat and pressure that made them to melt miles below the sea level (Erickson 59). The rain energy played a leading role in transporting these grains. The age of this fountain formation is 300 million years and its height is approximately 10000 feet high. At the Morrinson, there were the lyons and lykins formations that were formed about 251 million years ago. With respect to color the formations comprise of green, gray and maroon clay stone as well as mudstone. This formation was necessitated by movement and deposition of grains. There is also the presence of fossil deposits including dinosaur bones. This is exemplified by their wavy layers of muddy limestone that is indicative of stromatolites. The movement of the grains is attributed to rain energy that is also responsible for the weathering process. Their size according to Erickson is 400 feet thick (Erickson 59). With respect to the period of formation, it is a bit difficult to tell because this is largely depended on the kind of sediment carried in suspension as well as how well this is deposited. A walk through the Dakota formation offered useful insights regarding sandstone formation. In this, there was a continuity of various sandstone beds located at distinct spots along the road. Also, there were different sedimentary structures. These variations in the layers imply that the process of formation is continuous and not static. Notably, each layer was formed during a specific period with the bottommost layer having been formed earlier than the topmost layer. This shows that the process of deposition is continuous and being experienced even today. This is because the rain energy that necessitated previous depositions is still being experienced in the region. This structure also offers useful information about the deposition rate experienced in distinctive years. Notably, the layers differ considerably in size. This shows that the

Ebola Virus: Structure, Pathogenesis and Treatment

Ebola Virus: Structure, Pathogenesis and Treatment Named after the river valley in Zaire, now known as the Democratic Republic of Congo, where it was first recognized, Ebola began its publicity in the spotlight of an epidemic. It is one of two members of RNA viruses called Filoviridae. Filoviridae were first discovered 9 years before the initial outbreak of Ebola, in 1967, in workers who were exposed to blood from African green monkeys imported from Uganda that had the Marburg virus [6]. The family Filoviridae constitutes, together with the families Paramyxoviridae and Rhabdoviridae, the order Mononegavirales. Within the family there is a single genus, filovirus, and a separation into two sero-/genotypes, Marburg and Ebola [6]. Filoviruses are classified as Biological Level 4agents [5] based on their high mortality rate, person-to-person transmission, potential for aerosol infectivity, and absence of vaccines and chemotherapy [6]. There are five identified subtypes of the Ebola virus. Four of the five have caused disease in humans: Ebola-Zaire, Ebola-Sudan, Ebola-Ivory Coast and Ebola-Bundibugyo. The fifth, Ebola-Reston, has caused disease only in primates [2]. In 1976, the first subtype of Ebola was discovered, Ebola-Zaire. A local was admitted to a hospital in Zaire with a fever. The nurse assumed he had malaria and gave him a quinine shot. When the patient went home he died and a traditional African funeral was organized. In preparation, the woman from his family removed the blood from his body with their bare hands; most of the women died shortly after [4]. Meanwhile, the nurses at the hospital reused the needle for the quinine injection without sterilizing it, spreading the virus to everyone who came in contact with it. A doctor was called in to show how to sterilize their needles, purify their water, and give tips on how to bury the bodies that were now piling up. Quarantine followed after an autopsy was performed on a corpse and was held until every person who had contracted the virus had died [4]. Ebola-Zaire spread through the hospitals through reused needles and dead bodies, claiming an average 82.6% fatality rate from 1976 to 2003 [5]. The Zaire strain claims the most outbreaks and highest fatality rate of any strain of Ebola virus, although, it is not the only strain to take lives. As the Ebola-Zaire strain was being discovered the Ebola-Sudan strain also emerged. The first case appeared in a worker exposed at a cotton factory. The second case caused the death of a nightclub owner when he was introduced to an unsterilized needle [4]. Scientists were able to isolate these events, but a reemergence in the same location cased a smaller epidemic to occur just 3 years later in 1979. It rested at an overall 53.76% fatality rate spanning from 1976 to 2003 [5]. Ebola-Reston caused disease in a group of Macaques; some of the people exposed to the virus developed antibodies and none became ill [1]. The Ebola-Ivory Coast strain has only one known case of infection, that of a scientist dissecting a wild chimpanzee in 1994. The scientist fully recovered from the strain. Given the low infection rate, Ebola virus natural habitat s to this day remain unknown [2]. Structure Seen through an electron micrograph, the Ebola virus appears as long rods, 800-1000 nanometers in length. The filamentous structure is often found in a distinguishing U-shape arrangement, but is pleomorphic; meaning it can take on many shapes. Other shapes include branched, circular, or a 6 shape. The outer envelope of the virion is covered in small spikes, made of virally encoded glycoproteins [12]. These spikes are 7nm long, spaced 10nm apart, and allow the virus to attach itself to host cells. Ebola virus is an enveloped negative-sense RNA virus which is associated with zoonotic infections in humans [8]. Its genome consists of a single-stranded molecule of non-segmented, negative-sense RNA. The RNA is noninfectious, not polyadenylated, and complementary to polyadenylated viral subgenomic RNA species [6]. Gene signals are distinct by transcriptional start signals at their 3à ¢Ã¢â€š ¬Ã‚ ² (3à ¢Ã¢â€š ¬Ã‚ ²-CUNCNUNUAAUU-5à ¢Ã¢â€š ¬Ã‚ ²) and the termination signals at their 5à ¢Ã¢â€š ¬Ã‚ ² (3à ¢Ã¢â€š ¬Ã‚ ²-UAAUUCUUUUU-5à ¢Ã¢â€š ¬Ã‚ ²) end [6]. The RNA is enclosed by a capsid known as the nucleocapsid. The nucleocapsid is formed by viral proteins, primarily VP24 and VP35. The space between the outer viral envelope and the nucleocapsid is known as the matrix space. Several viral proteins are located in the matrix space. Although little is known about the molecular mechanics of filoviruses, scientists focus on the mechanics of viral proteins as they are thought to function p rimarily as immune antagonists. Viral protein 24 (VP24), functions primarily to inhibit a signaling pathway known as JAK-STAT. The JAK-STAT pathway is a secondary method of transmitting information from chemical signals outside the cell, through the cellular membrane and into the cell. By inhibiting this signaling pathway, several cellular activities are disrupted including transcription. Studies have identified several regions within VP24 that are important for nucleocapsid formation [8]. As part of the bodys first line of defense against viral infections, interferons, which are released by lymphocytes during a non-specific immune response, disrupt a viruss ability to replicate. Viral protein 35 (VP35) is thought to play a central role in the synthesis of viral RNA, serving as an interferon antagonist [12]. The degree of interferon antagonist production is said to determine the pathogenicity of the virus and may account for the varying degrees of virulence among different strains of the Ebola virus [12]. Additionally, VP35 is critical for viral replication, suppression of RNA silencing, and nucleocapsid formation [8]. The viral protein 30 (VP30) is known to act as a transcription activator. Studies have suggested that VP30 halts the host cell transcription complex at its start site allowing the Ebola virus transcription to begin [13]. A nonstructural glycoprotein has only been discovered with viruses of the Ebola type. This protein, designated sGP, shares ~ 300 N-terminal amino acids with glycoprotein, but has a different C terminus (~70 amino acids) containing many charged residues as well as conserved cysteines [6]. Ebola virus glycoproteins, specifically the envelope-glycoprotein and the secretory-glycoprotein, play critical roles in the pathogenesis of the virus. The envelope-glycoprotein is responsible for receptor binding and fusion of the virus with host cells. Because Ebola is an enveloped virus, cleavage activation of membrane glycoproteins is essential for fusion between the viral envelope and the host cell membrane. This fusion allows the virus entry into host cells. The secretory-glycoprotein is secreted from infected cells [12]. Glycoproteins can also produce cytotoxicity by inducing cell rounding and detachment of cell surface integrins [9]. Specific cells targeted by Ebola virus differ depending on the strain of virus. Studies have shown glycoproteins of Zaire Ebola virus induced pathogenic changes in endothelial cells in both human and primate cells, where Reston Ebola virus glycoproteins induced similar effects in the primate cells but not in the human cells [12]. Endothelial cell dysfunction is thought to explain hemorrhagic characteristic of filovirus infections [12]. Often the proteins target the endothelial cells lining the blood vessel wall, which eventually leads to internal bleeding. Replication Replication of RNA viruses differ from that of DNA viruses in several ways. One important difference is that replication occurs in the cytoplasm of the host cell, and not in the nucleus. The virion then releases an enzyme into the cytoplasm, known as RNA-dependent RNA transcriptase, to begin transcription of positive-RNA. This positive strand of RNA then acts as the template for viral protein translation [7]. The virus proceeds to integrate itself into the DNA of the host cell allowing the viral RNA to become part of the host cells genetic material. The virus (at this point called a prophage) now can replicate every time the host cell replicates. Ebola virus replicates via both lysogenic and lytic phases. The lysogenic cycle is a process in which the virus enters the host cell but doesnt immediately destroy it. The virus enters through endocytosis in which the entire encapsidated virion is engulfed and released into the cytoplasm of the cell. After some time, the prophage is excised from the chromosome and the cell reenters the lytic phase, where the host cell lyses and newly assembled virions are released. At this point, symptoms of viral infection become evident [13]. Pathogenesis and Manifestation The Ebola causes the disease Ebola hemorrhagic fever. Within the first week of contracting the virus, mild headaches occur. The headaches intensify and flu-like symptoms, backache and chills are present. Fever, diarrhea, fatigue, and nausea then set in. Vomiting may occur within the first two weeks. By the end of two weeks, coughing and vomiting of blood occurs. Late symptoms arise. Blood purges from the mouth and rectum; eyes, ears, and nose follow. The eyes begin to inflame and the genitals swell. Rash overtakes the body, often containing blood. Seizures, coma, and delirium ensue. Death commonly comes from shock rather than blood loss [10]. Hemorrhaging is generally found macroscopically in most organ systems in human death scenarios. Focal necrosis in the liver, lymphatic organs, kidneys, testes, and ovaries are observed under a microscope. Incubation of the virus ranges from 2 to 21 days depending on the strain; the subtype Zaire is 4 to 16 days [6]. Treatment There is no known cure or standard treatment for Ebola hemorrhagic fever. Antivirals generally given to fight similar viral infections do not work well against the Ebola virus. Those who are infected can only receive supportive treatment for their symptoms until their body is able to fight off the virus. Most importantly, the patients blood volume and electrolytes are maintained to prevent the patient from going into shock. Fever, blood pressure, and oxygen levels are also monitored. The best option is to prevent infection through early diagnosis and isolation when outbreaks occur. Although cases are rare, vaccines can be a vital tool. Filoviruses can be harvested from wild monkeys in possibly infected areas to process for future vaccines. Epidemiology and Avoidance Since the natural reservoirs are unknown, prevention is merely suggestion. Wearing protective equipment such as gloves, masks, goggles, gowns, and practicing sterilization is recommended when in contact with the virus. When traveling to epidemic areas, its important to wear such equipment, and learn of possible symptoms as a preventive measure. The goal is to avoid contact with blood or secretions of any patient, as person-to-person contact is the main route of infection in human outbreaks. Premise concludes an infected animal is the primary determinant for contracting Ebola virus. Transmission can occur from direct contact with blood and/or secretions prevalent when caring for the infected [3]. History of the virus shows that nosocomial transmission provides high outbreak potential when sterilization is not practiced consistently. In lab setting, research suggests Ebola has the ability of spreading through airborne particles, but this type has not been documented among humans in a real-world setting [2]. In the case of a diagnosis, several infectious diseases need to be considered before making a proper diagnosis of filovirus. Detection can be done in the lab by measuring the host-specific immunological response to the infection, or by detecting viral antigens and genomic RNA in the infected host [6]. Conclusion The Ebola virus poses significant threat to humans and animals. Although the incidence of outbreak is low, the infection is very serious and often fatal. So far, Ebola has been confined and isolated but there is always a risk of it spreading rapidly to the rest of the world. Without effective treatment and prevention the threat is enhanced. More extensive knowledge is needed to understand how the virus spreads and its development, specifically Ebolas natural reservoir. Therefore, while traveling the world, people should be aware of the threats from the Ebola virus in order to avoid infection, and hopefully scientists will do their best to develop a treatment and vaccination. McDonalds in Beijing: Localization of Americana McDonalds in Beijing: Localization of Americana Summary: According to me the Author talks about the recent changes in the Chinese society and the new tendency to adopt the foreign culture influences and transform them into local institution which was restricted by the Chinese political system during the Maoist era. The important points made in the article are as follows: Acceptance of foreign culture influences. Beijing customers are the active partners in the process of localisation. Representation of McDonalds as Americana and the promise of modernisation. People patronize McDonalds to experience a moment of equality. Making experience at McDonalds restaurants exotic, American, and to a certain extent, modern. Genuineness of McDonalds food that is being identical to its American counterpart. Attraction to McDonalds by its American style rather then its food. McDonalds interpretation of its food as a foreign form of xianbing. The culture of fast food attracting the Beijing consumers. A way to take part in transnational cultural system. At McDonalds, eating environment is considered as romantic and comfortable. McDonalds experience is treated as a chance to explore American culture and give their young one a special treat. McDonalds representation as a symbol of American Culture has led them to accept new patterns of behaviour. Willingness to accept the exotic culture and social behaviour in general. McDonalds treated as a place to gain status. Efforts made to adapt Chinese cultural settings. McDonalds as a place to hang out McDonalds creating a family atmosphere for Beijing customers. Personal interaction with customers. Beijing customers want their children to learn American culture. Finally the author concludes saying, McDonalds has transformed into middle class family establishment, where people can enjoy their leisure time and experience a Chinese version of American culture. Critical Review I think that the article is relevant in todays world and the localization process mentioned by the author in the article. For any multinational company it is necessary that they try to adopt the home countrys culture i.e. tries to bring the home culture in their goods and services. As said by Mingsheng Li, a senior lecturer in the Department of Communication, Journalism and Marketing at Massey University in Wellington, New Zealand, the degree of localization largely determines the degree to which a business succeeds or fails in a given country. The more the company works toward localization, the more likely it will be successful. It is necessary to understand ones culture and traditions and respect their tastes. But what is localization? To attract the target market, a product is made linguistically and it is culturally appropriate. When a company plans for global expansion, it is involved in the process of communication with local customers. Therefore it is necessary for the company to get familiar with local culture, study different customs, and make proper adjustments to their strategies according to the varied response of customers. The best example would be McDonalds in India. Majority of people in India are vegetarian. So McDonalds introduced range of vegetarian food in their outlet with the added flavor of American culture in it. McDonalds also priced their product according to the income of common people in India. Indian consumers were aware f the fast food culture, but the fast food in India was unhealthy and unhygienic. Introduction of McDonalds in India brought about the change in the fast food culture of India. The burgers were priced at Rs 20 which was affordable for an average middle class family. If McDonalds did not adopted localization strategy in China i.e. if they did not adopted the Chinese culture and traditions and the consumers taste, it was a failed project and the people of china would have banned it just like the French company Carrefour, hypermarket chain with more than 100 stores in major cities in China. The company had donated a large sum of money to the Dalai Lama. Calling for a boycott against French goods, Chinese nationals also called for a boycott against tourist travel to France. (Mingsheng Li, a senior lecturer in the Department of Communication, Journalism and Marketing at Massey University in Wellington, New Zealand). According to the article presented by the author it talks about the recent changes in the Chinese society and the new tendency to adopt the foreign culture influences and transform them into local institution which was restricted by the Chinese political system during the Maoist era. I strongly agree with the article and its process of localization strategy. The brand name of McDonalds was already there in the minds of Beijing customers. And before the McDonalds entered the Chinese market, the people of Beijing were fond of the American style and its culture. They were keen to learn the American or the Western culture. And when McDonalds entered the Chinese market on 23rd of April 1992, it served more than 40000 customers on the first day. This shows that the Beijing consumers were waiting for such kind of change in China, where they can experience the American or the Western culture. McDonalds has always been a fast food restaurant. The fast food in China was expensive and unhealthy. As mentioned in the article, in the eyes of the Beijing customers McDonalds represents Americana and the promise of modernisation. People also patronize McDonalds to experience the moment of equality. But McDonalds mad sure that they follow Chinese culture and Tradition and also keep up with the taste of the consumers to be successful in Chinese market. Some of the strategy adopted by McDonalds to attract the customer is Online chats Madden, Normandy; Wentz, Laurel. Advertising Age, 7/31/2006. For its its growth strategy in mainland China, McDonalds has created a live online chat series with the popular portal Sina and Askme.com.cn, a website launched by McDonalds in the mainland. Consumers can interact with leading sports, entertainment and business figures. The first one-hour episode Aug. 1 in Beijing will feature Houston Rockets basketball star and Shanghai, China, native Yao Ming, who signed a multiyear global partnership deal with McDonalds in 2004. The online initiative has no target age group, The program aims to provide consumer-focused education and encourage active, balanced lifestyles, but also be seen as an effort to ward off potential concerns about the nutritional content of fast food in general in China. Opens drive-through in China Madden, Normandy, Wentz, Laurel, Advertising Age, 00018899, 1/30/2006. Chinas rapid transformation into a car culture had led McDonalds to open drive thru in China. Drive-through sites, which account for a large proportion of McDonalds sales in the U.S., reflect Chinas rapid transformation into a car culture. With almost 6 million automobile sales last year, China has surpassed Japan and is now second only to the U.S. in annual car sales in the year 2006. This kind of strategy is a sign of bringing the American culture in China. But they are keeping in mind about the culture and traditions of China.

Essay --

Diabetes mellitus is a chronic metabolic disease characterized by high blood glucose levels (hyperglycemia) due to absolute (Type 1 diabetes) or relative (Type 2 diabetes) deficiency of insulin hormone (World Health Organization, 1999). Diabetes affects almost every organ system in the body due to metabolic problems caused by hyperglycemia, especially in undiagnosed or uncontrolled individuals (World Health Organization, 1999). Until recently it was believed that diabetes affected mainly developed countries, but recent research reveals an increase in the number of type 2 diabetes cases in developing countries (Chuang, 2002; Kinra, 2010; Narayanappa, 2011). Diabetes is associated with complications such as cardiovascular diseases, renal failure, loss of vision and neurological impairment, which can lead to a chronic disease state and even death (American Diabetes Association, 2004). The World Health Organization (WHO) estimates that more than 350 million people worldwide have diabetes. Almost 80% of deaths caused by diabetes occur in countries with low income. According to WHO, India is currently the country most affected by this disease with more than 32 million diabetic patients (Mohan, 2005). Background Insufficient response to insulin in what causes diabetes. The pancreas, an accessory gland of the digestive system, is the organ that produces insulin (ref Human Biology Book). The pancreas has a dual function because it features as both an endocrine and an exocrine gland. The part of the pancreas with endocrine function is organized in cell clusters called islets of Langerhans, which contains four main cell types that can be classified according to their secretion: alpha cells secrete glucagon, beta cells secrete insulin, del... ...cose multiple times each day and dealing with the various highs and lows (both physical and emotional) of life with diabetes can make all the difference. Conclusions To prevent diabetes related morbidity and mortality, there is an immense need of dedicated self-care behaviors in multiple domains, including food choices, physical activity, proper medications intake and blood glucose monitoring from the patients. Though multiple demographic, socio-economic and social support factors can be considered as positive contributors in facilitating self-care activities in diabetic patients, role of clinicians in promoting self-care is vital and has to be emphasized. Realizing the multi-faceted nature of the problem, a systematic, multi-pronged and an integrated approach is required for promoting self-care practices among diabetic patients to avert any long-term complications. Essay -- Diabetes mellitus is a chronic metabolic disease characterized by high blood glucose levels (hyperglycemia) due to absolute (Type 1 diabetes) or relative (Type 2 diabetes) deficiency of insulin hormone (World Health Organization, 1999). Diabetes affects almost every organ system in the body due to metabolic problems caused by hyperglycemia, especially in undiagnosed or uncontrolled individuals (World Health Organization, 1999). Until recently it was believed that diabetes affected mainly developed countries, but recent research reveals an increase in the number of type 2 diabetes cases in developing countries (Chuang, 2002; Kinra, 2010; Narayanappa, 2011). Diabetes is associated with complications such as cardiovascular diseases, renal failure, loss of vision and neurological impairment, which can lead to a chronic disease state and even death (American Diabetes Association, 2004). The World Health Organization (WHO) estimates that more than 350 million people worldwide have diabetes. Almost 80% of deaths caused by diabetes occur in countries with low income. According to WHO, India is currently the country most affected by this disease with more than 32 million diabetic patients (Mohan, 2005). Background Insufficient response to insulin in what causes diabetes. The pancreas, an accessory gland of the digestive system, is the organ that produces insulin (ref Human Biology Book). The pancreas has a dual function because it features as both an endocrine and an exocrine gland. The part of the pancreas with endocrine function is organized in cell clusters called islets of Langerhans, which contains four main cell types that can be classified according to their secretion: alpha cells secrete glucagon, beta cells secrete insulin, del... ...cose multiple times each day and dealing with the various highs and lows (both physical and emotional) of life with diabetes can make all the difference. Conclusions To prevent diabetes related morbidity and mortality, there is an immense need of dedicated self-care behaviors in multiple domains, including food choices, physical activity, proper medications intake and blood glucose monitoring from the patients. Though multiple demographic, socio-economic and social support factors can be considered as positive contributors in facilitating self-care activities in diabetic patients, role of clinicians in promoting self-care is vital and has to be emphasized. Realizing the multi-faceted nature of the problem, a systematic, multi-pronged and an integrated approach is required for promoting self-care practices among diabetic patients to avert any long-term complications.

The Messenger Eulogy

I Father O’reilly am privileged to have gathered amongst you all today, to give another perspective of a man who was not â€Å"just Ed†. He never gave himself great value but in my eyes he was a saint walking among us. I will never forget the moments and favours that Ed has shared with me. Ed, as many would say was a useless cab driver but in truth, I would say he was more of an inspiration and certainly it was an honour to have met this young gentleman. I still remember the day when I first met Ed. It was just a usual lonely night, when this young man showed up at my doorstep.I must say my first impressions of Ed were certainly very unique. Firstly the state of his jacket and not to mention the fact that he put four sugars in his coffee which made me slightly concerned. I never really got to ask Ed what he thought of me, I sort of knew he considered me a bit different to the rest especially being a priest and talking the way I do. There was that something about Ed whic h made him very special, I don’t know whether it was his innocent face or just the way he spoke but it seemed as if he had a passion to make things right in life.Words cannot describe how appreciative I am to this young boy, he has provided me a new perspective on how to live life. Ed visited me on a couple of occasions sometimes with his two friends Audrey and Marv. It didn’t take him long to realise that there weren’t many people who would visit my church. Ed took this matter into his own hands and it seemed as if he was determined to find a way to fix my problem. It was only a couple of days after visiting me on Sunday when Ed came barging through the front door with an idea on how to get people into my church.I must say I was shocked when I first heard the idea providing free beer in the church. I still remember the first thing I said to Ed was that I don’t have the money to cover the costs of such an aactivity. Ed ironically said to me â€Å"just ha ve a little faith† and walked away. I wondered at this point as to why he is doing so much for me when I barely even knew him from a bar of soap. There was certainly something which was pushing Ed to do all this for me but I never tried to interfere with his reasons. The next time I met Ed was on the day of the party at the church.I don’t know how many faces Ed has put a smile to, but one thing I can say for sure is that the happiness I achieved from that one day alone was something I doubt will ever come along in my life again. The number of people I saw in my church that day was never to be seen before, although the most important moment for me was when I reunited with the one man who I was longing to talk to. If I had the chance to change one thing with Ed, then that would be letting him know how grateful I am of all he has done for me. Besides what Ed has done for me, I have also heard about what he has done for others.The one I have heard about the most is the ice cream he bought for a lonely mother. It is certainly great to see that there are still people out there who are willing to go out of their way to help others. From the bottom of my heart I again would like to thank you for everything you have done for me Ed. Others may call you average, ordinary or even useless but to me you will always remain a saint. I still don’t know what your motivation was behind all that you have done for me Ed, but all I will say is that may there be more men like you in this world. May your soul rest in peace, god bless.

Every Grain of sand Essay - 1368 Words

poem tells a story within its words, even if it is not directly stated. Nearly every word and phrase in a poem, and even its punctuation has a meaning and a message that the author is trying to send across to the reading or listening audience. Not always is it easy to immediately understand what the poet is trying to say, but within the words and punctuation, over time and with analysis, interpretation is possible. Poetry is a group of so many words that a poet carefully chooses to show certain meaning. The song â€Å" Every Grain of Sand† that is written by Bob Dylan deserves to be called poetry because of his careful use of tone, symbolism, allusion, simile and enjambments. Tone is an important part of poetry. It sets the mood of the piece†¦show more content†¦3) represents this drowning hope that this person still has for a better life, even though there remains a feeling of despair, as it is said in line four. Dylan continues using nature in his symbolism in stanza 3, lines 9 and 10, â€Å" Oh the flowers of indulgence and the weeds of yesteryear, / Like Criminals, they have choked the breath of conscience and good cheer.† The flowers of indulgence represent the temptations in life – drawing people to their beauty, while the weeds of yesteryear choking the breath of conscience and good cheer represent the numbing effects of over indulgence. Things that once seemed to make life great have been used so much that, after a while, they are no longer fulfilling, leaving emptiness in a person. Even as the narrator realizes this, temptation still draws them in. â€Å"I gaze into the doorway of temptation’s angry flame. / And eve ry time I pass that way I always hear my name† (4.13-14) shows this. The doorway represents an opportunity or a choice to follow a path that leads to an â€Å"angry flame,† which can represent evil and hell. The voices calling are the inner temptation that we all have for things that give us immediate satisfaction. Throughout the poem, Dylan uses symbols to represent God or a higher power. He refers to the sun as it â€Å"beat down upon the steps of time to light the way to ease the pain of idleness and the memory of decay† (3.11-12), representing a force that guides us through our pain and tries to make life more bearable.Show MoreRelatedEssay scientific method1136 Words   |  5 Pagescrystal were absorbed by H2O with some bubbles at bottom while larger crystals were slowly beginning to break down. C. Appearance of sand Dry: Size was 1mm-1.5mm, pink, grey, brown, and opaque in color. Semi circulating ovals, jagged edges with hard and uneven surfaces. Appeared to be sharp and most of granules were different in origin. Wet: H2O encapsulated sand, most diverted to out edges forming a ring effect and none were dissolved. D. 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